The acanthocyte-echinocyte differential

The acanthocyte-echinocyte differential: The example of chorea-acanthocytosis.

Acanthocytes are a distinct structural (and functional) entity compared to echinocytes. The differential, however, is not always clear. A summary of morphologic characteristic to make a clear distinction is provided, using the blood of a rare neurologic disease with acanthocytic transformation of red blood cells.

In Vitro Protective Effect of Phikud Navakot Extraction on Erythrocyte

Phikud Navakot (PN), Thai herbal remedy in National List of Essential Medicines, has been claimed to reduce many cardiovascular symptoms especially dizziness and fainting. Apart from blood supply, erythrocyte morphology, in both shape and size, is one of the main consideration factors in cardiovascular diseases and may be affected by vascular oxidative stress. However, little is known about ant...

Effectsof the AntitumorDrugAdriamycinon HumanRed BloodCell Discocyte- EchinocyteTransitions1

The antitumor drug Adriamycin, when preincubated with hu man red blood cells (discocytes) for 10 min, prevented the formation of echinocytes induced by the calcium ionophore A23187 in the presence of 0.2 rriM calcium. The degree of protection was concentration dependent and was >90% at 10 UM Adriamycin. Adriamycin did not interfere with the accumula tion of calcium induced by a 5 MMconcentratio...

Spherocyte shape transformation and release of tubular nanovesicles in human erythrocytes.

We have studied dodecylmaltoside-induced echinocyte-spheroechincyte-spherocyte shape transformation and membrane vesiculation using transmission electron microscopy (TEM) on freeze-fracture replicas. It is indicated that spherical erythrocyte shape at higher dodecylmaltoside concentration is formed due to loss of membrane in the process where small, mostly tubular nanovesicles are released pred...

Morphology of normal erythrocyte and acanthocyte using Nomarski optics and the scanning electron microscope.